Engineering of a mammalian cell line for reduction of lactate formation and high monoclonal antibody production

Biotechnology and Bioengineering ◽

10.1002/1097-0290(20010105)72:1<55::aid-bit8>3.0.co;2-4 ◽

2000 ◽

Vol 72 (1) ◽

pp. 55-61 ◽

Author(s):

Keqin Chen ◽

Qian Liu ◽

Liangzhi Xie ◽

Phillip A. Sharp ◽

Daniel I. C. Wang

Keyword(s):

Monoclonal Antibody ◽

Cell Line ◽

Mammalian Cell ◽

Antibody Production ◽

Mammalian Cell Line ◽

Monoclonal Antibody Production ◽

Lactate Formation

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Cell line profiling to improve monoclonal antibody production

Biotechnology and Bioengineering ◽

10.1002/bit.25141 ◽

2013 ◽

Vol 111 (4) ◽

pp. 748-760 ◽

Author(s):

Sohye Kang ◽

Da Ren ◽

Gang Xiao ◽

Kristi Daris ◽

Lynette Buck ◽

...

Keyword(s):

Monoclonal Antibody ◽

Cell Line ◽

Antibody Production ◽

Monoclonal Antibody Production

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Use of Micro Bioreactor systems to streamline cell line evaluation and upstream process development for monoclonal antibody production

BMC Proceedings ◽

10.1186/1753-6561-5-s8-p14 ◽

2011 ◽

Vol 5 (S8) ◽

Author(s):

Steve R C Warr ◽

Jai Patel ◽

Rongzan Ho ◽

Katy V Newell

Keyword(s):

Monoclonal Antibody ◽

Cell Line ◽

Antibody Production ◽

Process Development ◽

Monoclonal Antibody Production ◽

Upstream Process

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Analysis of Nutritional Factors and Physical Conditions Affecting Growth and Monoclonal Antibody Production of the Hybridoma KB-26.5 Cell Line

Biotechnology Progress ◽

10.1021/bp950078x ◽

1996 ◽

Vol 12 (2) ◽

pp. 209-216 ◽

Author(s):

A. Sanfeliu ◽

J.J. Cairo ◽

C. Casas ◽

C. Sola ◽

F. Godia

Keyword(s):

Monoclonal Antibody ◽

Cell Line ◽

Antibody Production ◽

Monoclonal Antibody Production ◽

Nutritional Factors ◽

Physical Conditions

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Rapid automated selection of mammalian cell line secreting high level of humanized monoclonal antibody using Clone Pix FL system and the correlation between exterior median intensity and antibody productivity

Electronic Journal of Biotechnology ◽

10.2225/vol14-issue2-fulltext-7 ◽

2011 ◽

Vol 14 (2) ◽

Author(s):

Suba Dharshanan ◽

Heilly Chong ◽

Cheah Swee Hung ◽

Zulkeflie Zamrod ◽

Nazlee Kamal

Keyword(s):

Monoclonal Antibody ◽

Cell Line ◽

Mammalian Cell ◽

Mammalian Cell Line ◽

Humanized Monoclonal Antibody ◽

Antibody Productivity ◽

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Human lymphoblastoid cell line for hybridoma generation and monoclonal antibody production for tetanus treatment

Vaccine ◽

10.1016/0264-410x(86)90065-4 ◽

1986 ◽

Vol 4 (2) ◽

pp. 132

Keyword(s):

Monoclonal Antibody ◽

Cell Line ◽

Antibody Production ◽

Lymphoblastoid Cell Line ◽

Monoclonal Antibody Production ◽

Human Lymphoblastoid Cell ◽

Human Lymphoblastoid Cell Line

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Rescue of human monoclonal antibody production from an EBV-transformed B cell line by fusion to a human-mouse hybridoma

Journal of Immunological Methods ◽

10.1016/0022-1759(84)90392-2 ◽

1984 ◽

Vol 70 (1) ◽

pp. 83-90 ◽

Author(s):

S.K.H. Foung ◽

S. Perkins ◽

A. Raubitschek ◽

J. Larrick ◽

G. Lizak ◽

...

Keyword(s):

Monoclonal Antibody ◽

B Cell ◽

Cell Line ◽

Antibody Production ◽

Human Monoclonal Antibody ◽

Monoclonal Antibody Production

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Characterization of soy protein hydrolysates and influence of its iron content on monoclonal antibody production by a murine hybridoma cell line

Biotechnology Progress ◽

10.1002/btpr.3147 ◽

2021 ◽

Author(s):

Leïla Djemal ◽

Joerg Hagen ◽

Harald Kolmar ◽

Véronique Deparis

Keyword(s):

Monoclonal Antibody ◽

Cell Line ◽

Antibody Production ◽

Soy Protein ◽

Iron Content ◽

Protein Hydrolysates ◽

Monoclonal Antibody Production ◽

Soy Protein Hydrolysates

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Studies on monoclonal antibody production by a hybridoma cell line (C1E3) immobilised in a fixed bed, porosphere culture system

Journal of Biotechnology ◽

10.1016/0168-1656(90)90056-h ◽

1990 ◽

Vol 15 (1-2) ◽

pp. 129-145 ◽

Author(s):

A.J. Racher ◽

D. Looby ◽

J.B. Griffiths

Keyword(s):

Monoclonal Antibody ◽

Cell Line ◽

Antibody Production ◽

Culture System ◽

Fixed Bed ◽

Monoclonal Antibody Production

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Cell line-specific control of recombinant monoclonal antibody production by CHO cells

Biotechnology and Bioengineering ◽

10.1002/bit.22769 ◽

2010 ◽

Vol 106 (6) ◽

pp. 938-951 ◽

Author(s):

Peter M. O'Callaghan ◽

Jane McLeod ◽

Leon P. Pybus ◽

Clare S. Lovelady ◽

Stephen J. Wilkinson ◽

...

Keyword(s):

Monoclonal Antibody ◽

Cell Line ◽

Antibody Production ◽

Cho Cells ◽

Monoclonal Antibody Production ◽

Recombinant Monoclonal Antibody ◽

Specific Control

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A Different Perspective: How Much Innovation Is Really Needed for Monoclonal Antibody Production Using Mammalian Cell Technology?

New Bioprocessing Strategies: Development and Manufacturing of Recombinant Antibodies and Proteins - Advances in Biochemical Engineering/Biotechnology ◽

10.1007/10_2018_59 ◽

2018 ◽

pp. 443-462 ◽

Author(s):

Brian Kelley ◽

Robert Kiss ◽

Michael Laird

Keyword(s):

Monoclonal Antibody ◽

Mammalian Cell ◽

Antibody Production ◽

Monoclonal Antibody Production ◽

Cell Technology

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